Ingredient Page
13 High Quality
Natural Ingredients
Resveratrol

A powerful plant compound that helps reduce inflammation at the cellular level, supporting heart health, longevity, and immune function.

Resveratrol
Protects cells and supports healthy aging.

A powerful plant compound that helps reduce inflammation at the cellular level, supporting heart health, longevity, and immune function.

L-Glutamine

An essential building block that supports cellular health throughout your body. L-Glutamine helps maintain the integrity of your digestive system and supports your body's natural recovery processes, helping you bounce back faster from daily activities.

L-Glutamine
Supports digestive health and recovery.

An essential building block that supports cellular health throughout your body. L-Glutamine helps maintain the integrity of your digestive system and supports your body's natural recovery processes, helping you bounce back faster from daily activities.

Curcumin

The active compound in turmeric, curcumin helps reduce systemic inflammation, supporting joint health, immune response, and cellular protection.

Curcumin
Powerful natural compound for whole-body comfort.

The active compound in turmeric, curcumin helps reduce systemic inflammation, supporting joint health, immune response, and cellular protection.

L-Arginine HCI

Supports healthy blood flow, delivering oxygen and nutrients while helping flush out inflammatory toxins.

L-Arginine HCI
Boosts circulation for improved cellular nourishment.

Supports healthy blood flow, delivering oxygen and nutrients while helping flush out inflammatory toxins.

Matcha Green Tea Powder

Rich in polyphenols, matcha helps neutralize oxidative stress, which is a major driver of inflammation and aging.

Matcha Green Tea Powder
Provides lasting energy and cellular protection.

Rich in polyphenols, matcha helps neutralize oxidative stress, which is a major driver of inflammation and aging.

Choline L-Bitartrate

Enhances memory and supports brain health. This essential nutrient helps your brain cells communicate effectively, supporting mental clarity and focus. Choline also helps maintain healthy liver function and supports your body's natural energy production systems.

Choline L-Bitartrate
Enhances mental clarity and cognitive function.

Enhances memory and supports brain health. This essential nutrient helps your brain cells communicate effectively, supporting mental clarity and focus. Choline also helps maintain healthy liver function and supports your body's natural energy production systems.

Panax Ginseng Root Powder

A natural adaptogen that supports immune function, vitality, and endurance, helping your body stay strong and energized.

Panax Ginseng Root Powder
Boosts energy and strengthens resilience.

A natural adaptogen that supports immune function, vitality, and endurance, helping your body stay strong and energized.

GABA

Your body's natural calming messenger that promotes relaxation and comfort. GABA helps maintain balance in your nervous system, creating a sense of ease and supporting restful sleep. This natural compound helps you stay resilient against everyday stress.

GABA
Promotes relaxation and a sense of calm.

Your body's natural calming messenger that promotes relaxation and comfort. GABA helps maintain balance in your nervous system, creating a sense of ease and supporting restful sleep. This natural compound helps you stay resilient against everyday stress.

Boswellia Extract

A time-tested botanical that supports joint mobility and flexibility, helping you move freely and comfortably without limitations.

Boswellia Extract
Targets joint discomfort at the source.

A time-tested botanical that supports joint mobility and flexibility, helping you move freely and comfortably without limitations.

5-Hydroxytryptophan

Naturally boosts serotonin, the key neurotransmitter that regulates mood and physical comfort. Supports a positive outlook while helping you feel at ease throughout the day.

5-Hydroxytryptophan
Naturally uplifts mood and promotes comfort

Naturally boosts serotonin, the key neurotransmitter that regulates mood and physical comfort. Supports a positive outlook while helping you feel at ease throughout the day.

L-Serine

Supports mental clarity and mood regulation, helping your brain process and retain information while promoting a sense of well-being.

L-Serine
Enhances brain function and emotional balance.

Supports mental clarity and mood regulation, helping your brain process and retain information while promoting a sense of well-being.

Piperine

Enhances the effectiveness of other ingredients while providing its own comfort-supporting benefits. This natural black pepper extract helps your body absorb and utilize vital nutrients efficiently, maximizing the benefits of ProleevaMax's premium formula.

Piperine
Maximizes nutrient absorption for enhanced benefits.

Enhances the effectiveness of other ingredients while providing its own comfort-supporting benefits. This natural black pepper extract helps your body absorb and utilize vital nutrients efficiently, maximizing the benefits of ProleevaMax's premium formula.

Vitamin B6

A crucial vitamin that helps regulate inflammatory responses, supports energy production, and enhances immune resilience.

Vitamin B6
Essential for energy production and overall wellness.

A crucial vitamin that helps regulate inflammatory responses, supports energy production, and enhances immune resilience.

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CITATIONS/REFERENCES FOR EACH INGREDIENT

Choline Bitartrate

  1. Kusuda R, Carreira EU, Ulloa L, Cunha FQ, Kanashiro A, Cunha TM. Choline attenuates inflammatory hyperalgesia activating nitric oxide/cGMP/ATP-sensitive potassium channels pathway. Brain Res. 2020 Jan 15;1727:146567. doi: 10.1016/j.brainres.2019.146567. Epub 2019 Nov 26. PMID: 31783002; PMCID: PMC7054728.
  2. Moretti A, Paoletta M, Liguori S, Bertone M, Toro G, Iolascon G. Choline: An Essential Nutrient for Skeletal Muscle. Nutrients. 2020 Jul 18;12(7):2144. doi: 10.3390/nu12072144. PMID: 32708497; PMCID: PMC7400816.
  3. Sidhu N, Davies S, Nadarajah A, Rivera J, Whittington R, Mercier RJ, Virag L, Wang S, Flood P. Oral choline supplementation for postoperative pain. Br J Anaesth. 2013 Aug;111(2):249-55. doi: 10.1093/bja/aet031. Epub 2013 Apr 7. PMID: 23568851; PMCID: PMC3841409.

5-HTP (5-hydroxytryptophan)

  1. Maffei ME. 5-Hydroxytryptophan (5-HTP): Natural Occurrence, Analysis, Biosynthesis, Biotechnology, Physiology and Toxicology. Int J Mol Sci. 2020 Dec 26;22(1):181. doi: 10.3390/ijms22010181. PMID: 33375373; PMCID: PMC7796270.
  2. Caruso, I., Sarzi Puttini, P., Cazzola, M., & Azzolini, V. (1990). Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. The Journal of international medical research, 18(3), 201–209. https://doi.org/10.1177/030006059001800304
  3. Sarzi Puttini, P., & Caruso, I. (1992). Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study. The Journal of international medical research, 20(2), 182–189. https://doi.org/10.1177/030006059202000210
  4. Titus, F., Dávalos, A., Alom, J., & Codina, A. (1986). 5-Hydroxytryptophan versus methysergide in the prophylaxis of migraine. Randomized clinical trial. European neurology, 25(5), 327–329. https://doi.org/10.1159/000116030
  5. Shaw, K., Turner, J., & Del Mar, C. (2002). Tryptophan and 5-hydroxytryptophan for depression. The Cochrane database of systematic reviews, (1), CD003198. https://doi.org/10.1002/14651858.CD003198
  6. Kious, B. M., Sabic, H., Sung, Y. H., Kondo, D. G., & Renshaw, P. (2017). An Open-Label Pilot Study of Combined Augmentation With Creatine Monohydrate and 5-Hydroxytryptophan for Selective Serotonin Reuptake Inhibitor- or Serotonin-Norepinephrine Reuptake Inhibitor-Resistant Depression in Adult Women. Journal of clinical psychopharmacology, 37(5), 578–583. https://doi.org/10.1097/JCP.0000000000000754

L-arginine

  1. Morris CR, Kuypers FA, Lavrisha L, Ansari M, Sweeters N, Stewart M, Gildengorin G, Neumayr L, Vichinsky EP. A randomized, placebo-controlled trial of arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes. Haematologica. 2013 Sep;98(9):1375-82. doi: 10.3324/haematol.2013.086637. Epub 2013 May 3. PMID: 23645695; PMCID: PMC3762093.
  2. Rondón, L. J., Farges, M. C., Davin, N., Sion, B., Privat, A. M., Vasson, M. P., Eschalier, A., & Courteix, C. (2018). L-Arginine supplementation prevents allodynia and hyperalgesia in painful diabetic neuropathic rats by normalizing plasma nitric oxide concentration and increasing plasma agmatine concentration. European journal of nutrition, 57(7), 2353–2363. https://doi.org/10.1007/s00394-017-1508-x
  3. Hnia K, Gayraud J, Hugon G, Ramonatxo M, De La Porte S, Matecki S, Mornet D. L-arginine decreases inflammation and modulates the nuclear factor-kappaB/matrix metalloproteinase cascade in mdx muscle fibers. Am J Pathol. 2008 Jun;172(6):1509-19. doi: 10.2353/ajpath.2008.071009. Epub 2008 May 5. PMID: 18458097; PMCID: PMC2408412.
  4. Wu, T., Wang, C., Ding, L., Shen, Y., Cui, H., Wang, M., & Wang, H. (2016). Arginine Relieves the Inflammatory Response and Enhances the Casein Expression in Bovine Mammary Epithelial Cells Induced by Lipopolysaccharide. Mediators of inflammation, 2016, 9618795. https://doi.org/10.1155/2016/9618795

Gamma-Aminobutyric Acid (GABA) 99%

  1. Ngo DH, Vo TS. An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid. Molecules. 2019 Jul 24;24(15):2678. doi: 10.3390/molecules24152678. PMID: 31344785; PMCID: PMC6696076.
  2. Ngo DH, Vo TS. An Updated Review on Pharmaceutical Properties of Gamma-Aminobutyric Acid. Molecules. 2019 Jul 24;24(15):2678. doi: 10.3390/molecules24152678. PMID: 31344785; PMCID: PMC6696076.

Glutamine

  1. Samuel Wilson, Frances Wright, Marcus A. Carden, L-Glutamine Decreases Opioid Use in Individuals with Sickle Cell Disease and Chronic Pain: A Case Series, Blood, Volume 134, Supplement 1, 2019, Page 4849, ISSN 0006-4971, https://doi.org/10.1182/blood-2019-126179.
  2. Kim MH, Kim H. The Roles of Glutamine in the Intestine and Its Implication in Intestinal Diseases. Int J Mol Sci. 2017 May 12;18(5):1051. doi: 10.3390/ijms18051051. PMID: 28498331; PMCID: PMC5454963.
  3. Coqueiro AY, Rogero MM, Tirapegui J. Glutamine as an Anti-Fatigue Amino Acid in Sports Nutrition. Nutrients. 2019 Apr 17;11(4):863. doi: 10.3390/nu11040863. PMID: 30999561; PMCID: PMC6520936.
  4. Córdova-Martínez A, Caballero-García A, Bello HJ, Pérez-Valdecantos D, Roche E. Effect of Glutamine Supplementation on Muscular Damage Biomarkers in Professional Basketball Players. Nutrients. 2021 Jun 17;13(6):2073. doi: 10.3390/nu13062073. PMID: 34204359; PMCID: PMC8234492.

L-Serine

  1. ZHOU, X., ZHANG, H., HE, L., WU, X. & YIN, Y. 2018. Long-Term l-Serine Administration Reduces Food Intake and Improves Oxidative Stress and Sirt1/NFκB Signaling in the Hypothalamus of Aging Mice. Frontiers in Endocrinology, 9.
  2. YE, L., SUN, Y., JIANG, Z. & WANG, G. 2021. L-Serine, an Endogenous Amino Acid, Is a Potential Neuroprotective Agent for Neurological Disease and Injury. Frontiers in Molecular Neuroscience, 14.
  3. Sasahara, I., Yamamoto, A., Takeshita, M., Suga, Y., Suzuki, K., Nishikata, N., Takada, M., Hashimoto, M., Mine, T., Kobuna, Y., & Nagao, K. (2020). l-Serine and EPA Relieve Chronic Low-Back and Knee Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial. The Journal of nutrition, 150(9), 2278–2286. https://doi.org/10.1093/jn/nxaa156

Curcumin

  1. Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013 Jan;15(1):195-218. doi: 10.1208/s12248-012-9432-8. Epub 2012 Nov 10. PMID: 23143785; PMCID: PMC3535097.
  2. Binion DG, Heidemann J, Li MS, Nelson VM, Otterson MF, Rafiee P Vascular cell adhesion molecule-1 expression in human intestinal microvascular endothelial cells is regulated by PI 3-kinase/Akt/MAPK/NF-kappaB: inhibitory role of curcuminAm J Physiol Gastrointest Liver Physiol. (2009 Aug)
  3. Kumar A, Dhawan S, Hardegen NJ, Aggarwal BB Curcumin (Diferuloylmethane) inhibition of tumor necrosis factor (TNF)-mediated adhesion of monocytes to endothelial cells by suppression of cell surface expression of adhesion molecules and of nuclear factor-kappaB activationBiochem Pharmacol. (1998 Mar 15)
  4. Di Pierro F, Rapacioli G, Di Maio EA, Appendino G, Franceschi F, Togni S Comparative evaluation of the pain-relieving properties of a lecithinized formulation of curcumin (Meriva(®)), nimesulide, and acetaminophenJ Pain Res.(2013)
  5. Belcaro G, Cesarone MR, Dugall M, Pellegrini L, Ledda A, Grossi MG, Togni S, Appendino G Product-evaluation registry of Meriva®, a curcumin-phosphatidylcholine complex, for the complementary management of osteoarthritisPanminerva Med.(2010 Jun)
  6. Belcaro G, Cesarone MR, Dugall M, Pellegrini L, Ledda A, Grossi MG, Togni S, Appendino G Efficacy and safety of Meriva®, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patientsAltern Med Rev. (2010 Dec)

Boswellia Extract (Boswellia serrata)

  1. Perry TA1, Weerasuriya A, Mouton PR, Holloway HW, Greig NH. Pyridoxine-induced toxicity in rats: a stereological quantification of the sensory neuropathyExp Neurol. (2004 Nov)

Piperine

  1. Gupta SC, Patchva S, Aggarwal BB. Therapeutic roles of curcumin: lessons learned from clinical trials. AAPS J. 2013 Jan;15(1):195-218. doi: 10.1208/s12248-012-9432-8. Epub 2012 Nov 10. PMID: 23143785; PMCID: PMC3535097.
  2. Tripathi AK, Ray AK, Mishra SK. Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials. Beni Suef Univ J Basic Appl Sci. 2022;11(1):16. doi: 10.1186/s43088-022-00196-1. Epub 2022 Jan 28. PMID: 35127957; PMCID: PMC8796742.

Matcha Green Tea Extract

  1. Kochman J, Jakubczyk K, Antoniewicz J, Mruk H, Janda K. Health Benefits and Chemical Composition of Matcha Green Tea: A Review. Molecules. 2020 Dec 27;26(1):85. doi: 10.3390/molecules26010085. PMID: 33375458; PMCID: PMC7796401.
  2. Dietz, C., & Dekker, M. (2017). Effect of Green Tea Phytochemicals on Mood and Cognition. Current pharmaceutical design, 23(19), 2876–2905. https://doi.org/10.2174/1381612823666170105151800
  3. Sachdeva AK, Kuhad A, Tiwari V, Arora V, Chopra K Protective effect of epigallocatechin gallate in murine water-immersion stress model of chronic fatigue syndrome Basic Clin Pharmacol Toxicol. (2010 Jun)
  4. Unno K, Furushima D, Hamamoto S, Iguchi K, Yamada H, Morita A, Horie H, Nakamura Y. Stress-Reducing Function of Matcha Green Tea in Animal Experiments and Clinical Trials. Nutrients. 2018 Oct 10;10(10):1468. doi: 10.3390/nu10101468. PMID: 30308973; PMCID: PMC6213777.

Panax Ginseng Root Powder

  1. Ratan ZA, Haidere MF, Hong YH, Park SH, Lee JO, Lee J, Cho JY. Pharmacological potential of ginseng and its major component ginsenosides. J Ginseng Res. 2021 Mar;45(2):199-210. doi: 10.1016/j.jgr.2020.02.004. Epub 2020 Mar 25. PMID: 33841000; PMCID: PMC8020288.
  2. Kim JH, Yi YS, Kim MY, Cho JY. Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases. J Ginseng Res. 2017 Oct;41(4):435-443. doi: 10.1016/j.jgr.2016.08.004. Epub 2016 Aug 18. PMID: 29021688; PMCID: PMC5628327.
  3. Braz, A. S., Morais, L. C., Paula, A. P., Diniz, M. F., & Almeida, R. N. (2013). Effects of Panax ginseng extract in patients with fibromyalgia: a 12-week, randomized, double-blind, placebo-controlled trial. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), 35(1), 21–28. https://doi.org/10.1016/j.rbp.2013.01.004
  4. Li MX, Wei QQ, Lu HJ. Progress on the Elucidation of the Antinociceptive Effect of Ginseng and Ginsenosides in Chronic Pain. Front Pharmacol. 2022 Feb 21;13:821940. doi: 10.3389/fphar.2022.821940. PMID: 35264958; PMCID: PMC8899510.

Resveratrol 98%

  1. Sahar Foshati;Mohammad Hossein Rouhani;Reza Amani; (2021). The effect of grape seed extract supplementation on oxidative stress and inflammation: A systematic review and meta‐analysis of controlled trials . International Journal of Clinical Practice, (), –. doi:10.1111/ijcp.14469
  2. Nallathambi R, Poulev A, Zuk JB, Raskin I. Proanthocyanidin-Rich Grape Seed Extract Reduces Inflammation and Oxidative Stress and Restores Tight Junction Barrier Function in Caco-2 Colon Cells. Nutrients. 2020 Jun 1;12(6):1623. doi: 10.3390/nu12061623. PMID: 32492806; PMCID: PMC7352846.
  3. Terra X, Valls J, Vitrac X, Mérrillon JM, Arola L, Ardèvol A, Bladé C, Fernandez-Larrea J, Pujadas G, Salvadó J, Blay M Grape-seed procyanidins act as antiinflammatory agents in endotoxin-stimulated RAW 264.7 macrophages by inhibiting NFkB signaling pathway J  Agric Food Chem. (2007 May 30)

Vitamin B6

  1. Bird R. P. (2018). The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis. Advances in food and nutrition research, 83, 151–194. https://doi.org/10.1016/bs.afnr.2017.11.004
  2. Du, X., Yang, Y., Zhan, X., Huang, Y., Fu, Y., Zhang, Z., Liu, H., Zhang, L., Li, Y., Wen, Q., Zhou, X., Zuo, D., Zhou, C., Li, L., Hu, S., & Ma, L. (2020). Vitamin B6 prevents excessive inflammation by reducing accumulation of sphingosine-1-phosphate in a sphingosine-1-phosphate lyase-dependent manner. Journal of cellular and molecular medicine, 24(22), 13129–13138. https://doi.org/10.1111/jcmm.15917
  3. Ghavidel-Parsa, B., Naeimi, A., Gharibpoor, F. et al. Effect of vitamin B6 on pain, disease severity, and psychological profile of fibromyalgia patients; a randomized, double-blinded clinical trial. BMC Musculoskelet Disord 23, 664 (2022). https://doi.org/10.1186/s12891-022-05637-7
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. The views and nutritional advice expressed by Lanfam LLC are not intended for the purpose of providing medical advice. Please always consult your health care provider if you are taking any medications or have any medical conditions. Individual results may vary.
** The natural foods depicted in our product images are inspired by ingredients found in Proleevamax.